Equipped with the updated 3.0-liter turbocharged V6 engine and a 7-speed S tronic dual-clutch transmission, the 2026 Audi S5 can accelerate from 0 to 60 mph in approximately 4.3 to 4.5 seconds, depending on the body style and testing conditions, assisted by the standard Quattro all-wheel-drive system. For buyers considering the Audi S5, that matters because it affects how easy the car is to live with, whether for commuting, family use, long-distance driving or ownership costs. The useful way to read this is not as an isolated specification, but as a clue to how the car will feel in real daily use.