Maintenance costs for an Audi S5 are typically higher than standard sedans, with an average annual cost between $900 and $1,200, as it requires specialized synthetic oil, high-performance brake components, and specific Quattro system fluid changes; however, the 2026 model often includes "Audi Signature Care" covering scheduled maintenance for the first three years. For buyers considering the Audi S5, that matters because it affects how easy the car is to live with, whether for commuting, family use, long-distance driving or ownership costs. The useful way to read this is not as an isolated specification, but as a clue to how the car will feel in real daily use.